With the collaboration of
Con la colaboración de

09.30 – 10:00 h

Registration

10:00 – 10:30 h

Welcome - Anna Bigas, CIBERONC Scientific Director

10:30 – 11:30 h

Keynote Lecture

Chairs: Mireia Ramos, Cristina Martínez

“Lecture Title” Ana Cuenda - Centro Nacional de Biotecnología (CNB)

11:30 – 12:15 h

Session I: Cancer Genomics, Epigenetics and Personalized Medicine

11:30 – 11:45 h

Identification of DNA damage repair (DDR) factors susceptible to be therapeutically approached in Ewing Sarcoma - Esther Cruz Zambrano

11:45 – 12:00 h

Methodogical comparision for tumor cell detection in Waldenström’s macroglobulinemia - Patricia Pérez Guijorro

12:00 – 12:15 h

CRISPR- and mutational signature-based assay in human cells to evaluate proofreading deficiency in POLE and POLD1 variants - Julen Viana Errasti

12:15 – 12:45 h

Coffee Break & Poster Session

12:45 - 13:30 h

Session II: Tumor Microenvironment and Stromal interactions

Chairs: Ester Munera, Marta Cano

12:45 – 13:00 h

Tumor-intrinsic GSK-3β orchestrates stromal remodeling and immune escape in colorectal cancer: unveiling a therapeutic opportunity - Aurora Rivas Crespo

13:00 – 13:15 h

Targeting Breast Cacer with Mitochondrial Inhibitors Delivered via Tunneling Nanotubes - Inés Saenz de Santa María

13:15 – 13:30 h

Aggressive Transcriptomic Landscape of Postpartum Breast Cancer and Potential Early Risk Signatures in Adjacent Normal Tissue - Regina Peña Enríquez

13:30 - 14:15 h

Round Table - Life After the PhD: Academia, Industry, and Beyond

Rosario Hervás - Merck España

Verónica Llorens - Centro de Investigación Principe Felipe (CPIF)

Javier Carmona - Vall d’Hebron Institute of Oncology (VHIO)

Paula Mayorga-Burrezo - Institut de Ciència de Materials de Barcelona (ICMAB)

14:15 – 15:15 h

Lunch Break

15:15 – 16:15 h

Keynote Lecture

Role of SWI/SNF alterations in cellular plasticity, tumor progression and treatment in lung cancer- Ignacio Varela (IBBTEC)

16:15 – 16:45 h

Pitch your Project

Disitamab Vedotin Outperforms Trastuzumab-Emtansine and Overcomes Secondary Resistance to HER2- TargetedDrugs in Breast Cancer - Mónica Redondo Puente

The Genomic Landscape of Bladder Cancer: Insights from Copy Number Alteration Profiles - Ane Moreno Oya

Patient-derived tumor tissue cultures (PDTTCs) as a new platform for assessing T cell engager efficacy in glioblastoma - Raffaella Lurlaro

16:45 - 17:30 h

Session III: Targeted Therapies and Resistance Mechanisms in cancer

16:45 - 17:00 h

High CD70 expression in newly diagnosed Folicular Lymphoma is linked to relapse and may be exploited through dual CD19 - CD70 CAR-T therapy - Maria Ros

17:00 - 17:15 h

Therapeutic Potential of a Lineal Polypeptide Nanocarrier in Ewing Sarcoma Using 3D Hydrogels - Carlos Estellés

17:15 - 17:30 h

Molecular mechanisms of high-fat diet as a risk factor for pancreatic ductal adenocarcinoma (PDAC) initiation and progression- Ana Galván del Rey

17:30 - 18:30 h

Sustainability Activity and Good Laboratory Practices

09:00-09:45 h

Session IV: Targeted Therapies and Resistance Mechanisms in cancer II

Chairs: Mikel Pujana, Pablo Ovejero

09:00 - 09:15 h

CD36-mediated lipid scavenging drives metabolic remodeling in B-cell lymphoma - Adrián Arnaiz Leché

09:15 - 09:30 h

SOS2 genetic ablation enhances the efficacy of pharmacologic SOS1 inhibition in KRASG12D driven LUAD - Pablo Rodríguez Ramos

09:30 - 09:45 h

PRC2 and MYC Pathways Drive Fetal Conversion in Drug-Tolerant Persister Cells - Ángela Montoto

09:45 – 10:15 h

Pitch your Project

Generation of Patient-Derive Organoides from Uterine Aspirates of Endometrial Cancer Patients as a Preclinical Modelfor Testing Novel Therapies - Sónia López Landrove

Fanca-Ko Mice Exhibit Age-Dependent High-Frequency Oral Cavity Lesion Development - Sonia del Marro

Single-cell Multiomics Based Multidimensional Flow Cytometry (MFC) for Measurable Residual Disease (MRD) Assessment in Patients (pts) With Acute Myeloid Leukemia (AML) - Carmen González

10:15 – 10:45 h

Coffee Break & Poster Session

10:45 - 11:45 h

Keynote Lecture

Chairs: Mireia Ramos, Ester Munera

"Lecture Title” Ana Río - IIS Fundación Jiménez Díaz (IIS-FJD)

11:45 - 12:30 h

Session V: Early cancer detection and Emerging Technologies

11:45 – 12:00 h

Biomimetic nanophotonic technologies for preclinical in vitro evaluation of cell immunotherapies - Raquel Gomes Rua

12:00 – 12:15 h

Plasma Exosomes from Individuals with HIV and Cancer Enhance Tumor Cell Proliferation and Migration - Asier Ureta

12:15 – 12:30 h

Proteomics Characterization Of Both Human And Microbiota Proteomes In Ffpe Colorectal Cancer Cohort Redefine The Colorectal Cancer Consensus Molecular Subtypes - Fernando Becerril

12:30 - 13:30 h

Workshop - Mental health in science

Derek Clougher - Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)

13:30 - 14:00 h

Closing Remarks, Awards & Quiz

14:00 – 15:00 h

Lunch